Sentence examples for front line regimen from inspiring English sources

Combination of platinum derivatives with paclitaxel is currently the standard front line regimen for patients with epithelial ovarian carcinoma, and represents also an active regimen in patients with metastatic breast or unknown primary carcinomas.

Combination of platinum derivatives (cisplatin or carboplatin) with paclitaxel is currently the standard front line regimen for patients with advanced epithelial ovarian carcinoma (EOC) after demonstration of superior survival in randomized clinical trials [ 1, 2].

Among 64 patients treated with platinum/gemcitabine combinations as front-line regimen, 8 patients (13%) had a median OS > 24 months.

The combination of pemetrexed plus cisplatin is considered the benchmark front-line regimen for this disease, based on a phase III trial in 456 patients that yielded a response rate of 41% and a median survival of 12.1 months.

Another trial with the same agents and dosages produced similar toxicity and a 20% response rate, which cannot be ignored as a second-line chemotherapy following a docetaxel-based front-line regimen (Kakolyris et al, 2001).

The combination of pemetrexed and cisplatin is considered the front-line regimen for this disease, yielding a response rate of 41% and a median survival of 12.1 months [ 2].

These data and others highlight the clinical concern that salvage regimens for relapsed/refractory patients may not be as effective in the era of rituximab usage in front-line regimens.

Five-year SFR was 25, 54, and 48%% for patients who never received rituximab, those who received the drug only at relapse and those treated with rituximab both in front line and rescue regimen, respectively (P = 0.007).

Different chemotherapy regimens in the front line as well in the palliative setting showed promising efficacy in first line as well in advanced disease [ 5– 7].

Various chemotherapy regimens in the front line as well in the palliative setting showed promising effect in first line as well in advanced disease for patients with NULMS [ 5– 7] as well as ULMS [ 10, 12].

The front line treatment for B-ALL involves an intense chemotherapy regimen with cure rate up to 80%.