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Once the tethered head binds successfully, and the motor achieves the 2-HB state [C], an unbinding gate is required to retain the front head on the MT, while promoting the release of the rear head.
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Gaze estimation with fixed front head pose based on GDBP is presented in Section 3, followed by experimental results with comparisons with other approaches.
The application of hindering loads to the kinesin stalk places a rearward load on its front head, and therefore can serve as a proxy for estimating the rate of detachment of the front head at the unbinding gate.
In the 2-HB state [C], inter-head tension exerts not only a forward load on the rear head, but also imposes a matching rearward load on the front head.
The data also suggest that there is no-substep per se and that stomping of the front head, as was proposed based on AFM images and an earlier fluorescence study, may not be an essential part of the stepping mechanism.
Turn the lugs on the front head a little at a time until you get the sound you want.
Then, sometime when all is quiet on the Western front, head across the street with a token gift that shows your fondness — a banana bread, say, or a remix of "Boom Boom Pow" by the Black Eyed Peas — and level with them: "You've been good neighbors, but the music is driving us nuts.
I was holding this hammer wrench up in front of my head on one of the nuts.
Let it go lower around the front of your head on one side.
Tune the front head in the same manner as the batter head, but turn the lugs another half turn to get a slightly higher tone on the front head.
This established an enclosure that put a chokehold on the Roman forces caught inside since their backline was forced forward and the front lines collided head-on with infantry.
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