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Second, as with any survey based on a convenience sample, the results obtained from this sample may not be a representative sample of all the pediatricians in the US.
First, we enrolled a highly self-selected sample of clinicians who were very high users of HDS before starting the course; results from this sample may not be generalizable to other groups of clinicians.
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Sequence information from a single sample may not be adequate for the detection of mutated virus.
These data from an inpatient sample may not be representative of patients with BED seen in other settings [ 64].
After this much data processing, the representative sample may not be so purely representative anymore.
The sample may not be drawn from the whole screen interval even with extended pumping times.
That is, the effect found in the sample may not be present in the actual population from which the sample was drawn.
Yet we know that analysis of a single sample may not be enough.
The uncertainty arising from sampling may not be under control, however, and the methods to evaluate it are still less well known.
Determinants of DNA yield from whole blood samples may not be the same as for buccal samples.
Insufficient patient samples would not cover all aspects of the metastases, thus gene signatures selected from small number of samples may not be credible enough.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com