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From these input parameters the interfacial shear strength between the TiAlN coating and ZIRLO™ substrate was inferred to be around 120 MPa.

From these input criteria an assay optimization procedure can be chosen to obtain a final assay where all the desired mutations/SNP's can be analysed (Figure 5A).

The Ka/Ks Calculator Tool calculated the multiple sequence alignment and the phylogenetic tree from these input sequences, translated the DNA-sequences to protein, calculated the alignment, transformed it back to DNA, and aligned it on codon boundaries for Ka/Ks calculation.

A random value from these input distributions was plugged in the model, and the corresponding expected costs and outcomes were calculated.

We ran half a million iterations of the model, producing the histogram in Figure 1 that approximates the probability density for the total number of cases that results from these input uncertainties.

After this process, a n × k matrix (LHS matrix) is generated, containing the n sampled sets of values for all the k model parameters, as showed by Figure 2, panel A. Starting from these input values, each row of the LHS matrix is used as an input to numerically integrate the system over the time interval T = [ t ini, t end], and thus producing n time-dependent model solutions.

From these inputs, a total of 4444 CML Reactions were derived, representing around 17% of the total input.

The inputs of the users are considered sensitive, personal information, and the server computes a function F from these inputs.

However, apart from these inputs, no additional financial resources were provided for implementation.

From these inputs, we sought to enrich centromere-specific CENP-A nucleosomes (henceforth referred to as 'centromeric CENP-A') using native immunoprecipitation (IP) for the inner kinetochore protein CENP-B.

In other words, once the dose-related biochemical and genomic steps in a pathway have been identified, it may be more feasible to work directly from these inputs rather than from predictions of downstream consequences obtained from TP models.