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Participants with serious medical conditions (e.g., cardiac arrhythmias) were excluded from the study because of possible confounding effects with regard to the physiological measurement.
Two cases were rejected from the study because of possible interpretation bias.
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Morbidly obese patients were excluded from the study because of the possible perturbation in the calculation of body surface corrected creatinine clearance.
For instance, it is possible that non-participants decided against participating in the study because of lack of a car or because they resided in locations situated farther away from where participants had to travel.
Of the 260 initial cohort volunteers, 22 (8.5%) were excluded from the study, because it was not possible obtain follow-up samples.
All values of hs-CRP which were higher than 10 mg/L were excluded from the study because such an elevation of hs-CRP might also result from a possible systemic infection.
The study became possible because of an unusual situation in Oregon.
The study design was possible because of flexibility in the curricula at these schools.
The study was conducted following a request from community representatives for an epidemiological study because of concern about possible adverse respiratory health effects on children of the petrochemical refinery's emissions in the surrounding neighbourhoods.
Comorbidities may prevent the physician from delivering optimal therapy because of possible treatment-related side effects.
Because of the study design, other possible confounders could not be taken into account.
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