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However, it retains a substantial affinity for HP that might result from the stabilization of the complex through the collaboration between the conserved BBXB motif in the core of the chemokine and the remaining positive charges in the yet highly cationic C-ter domain.
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The stabilization of the complex in presenescent VSMCs suggested that it may have a role in DNA damage signalling.
This may be due to the stabilization of the complexes due to the hydrophobic interactions between the LA moieties.
Subsequent interaction with the ligand induces flap closure and the stabilization of the macromolecular complex.
Functionally, HIV-mediated actin polymerization may be required to transiently block CXCR4 internalization for the stabilization of the fusion complex.
The viral polymerase protein PA and the nucleocapsid protein are important for the stabilization of the CPSF30 NS1 complex.
These data suggested that hydrophobic forces, rather than electrostatic interactions, are involved in the stabilization of the peptide-GSL complex.
The stabilization of the high-T phase of Li(CB9H10) was achieved by partially replacing (CB9H10)− complex anions with (CB11H12)− complex anions using a mechanical ball-milling technique (see the Methods section for details).
Thus, the stabilization of bFGF/HS/bFGFR complex, by supplying heparin and bFGF, may protect ECs from injury by high glucose or heparanase.
Being located at the lumenal surface of the enzyme, PS-C550 cytochrome acts as an insulator of the catalytic core from reductive attack and contributes to structural stabilization of the complex.
We initially also expected a stabilization of the complex upon light-activation and subsequent LOV dimerization.
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