Exact(9)
A trio composed of a nuclear family with an affected child, an affected parent, a non-affected parent (Fig. 2) and a distantly related affected family member from the same pedigree as many meioses from the trio as possible are sequenced.
When using multiplex cases from the same pedigree, we need to take into account correlations.
The pathological findings were consistent with Col3GP and identical to the lesions previously described in other dogs from the same pedigree [ 6].
This data was from the same pedigree as described previously but used SNP on all chromosomes rather than just chromosome 1.
In the second scenario, whether or not paired individuals are from the same pedigree, all kinship coefficients between pairs of individuals are estimated by genotyped variants.
In addition to the four affected puppies from the studied litter, three other Col3GP affected individuals from the same pedigree contributed to the serum analyses of PIIINP and C3, and eight healthy dogs of similar age, including four from the same pedigree, were used as control animals.
Similar(51)
If you are buying from a private seller, ask for the same pedigree materials.
Relative runtime changes are for the same pedigree and computer as in (2) above.
We have provided proof of principle of this approach by demonstrating low P values for phenotypic similarity between BPD cases from the same pedigrees and between unrelated cases with provisional clinical diagnoses of syndromic BPD, in which both groups are likely to share a causal genetic variant.
"He's the same pedigree as me.
The same pedigree fits one of the internal front-runners, James Gorman.
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