After GTP hydrolysis and release of EF-Tu, the cognate tRNA moves rapidly to A-site accommodation and peptidyl transfer, whereas a near-cognate tRNA that has 'survived' the initial selection is most likely to dissociate from the ribosome in the proofreading step.
We thank Dr. Alan Gibson from the Barrow Neurological Institute for proofreading the manuscript.
Most such mutations result from replication slippage that escaped the proofreading activity of mismatch repair systems [ 3].
While rapid binding can in principle be realized between proteins of single binding elements (e.g., driven by strong electrostatics), the proofreading emanating from the multiplicity and rapid repetition of many such events is what contributes to specific transport.
Our results show that the proofreading function of ε can be uncoupled from the SOS phenotypes.
His wife, Jane Fuller, is the head of the proofreading squad, when she is not running a group for children from divorced families, or doing other volunteer work.
The proofreading department was gay.
The notes are erratically introduced and the proofreading is sloppy.
XZ organizes the whole paper as well as the proofreading.
