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In response to the rumen challenge, intake of LC increased from the baseline level of 18.1% of total daily dry matter intake to 38.3% for that day.
The depth of anesthesia was assessed by monitoring blood pressure responses to noxious stimulation; supplementary anesthetic was administered when necessary to ensure the absence of gross (>20% from the baseline level) blood pressure fluctuations.
The mean rate of evoked firing of these units at each time point after formalin administration did not differ from the baseline level (4.2 ± 0.5 spikes/stimulus, N = 9, P > 0.05, Wilcoxon signed rank test) and was comparable to the discharge rate of the saline-treated cells (P > 0.05, Mann–Whitney Wilcoxon test; Fig. 3b).
However, this value did not significantly differ from the baseline level (4.3 ± 0.6 spikes/stimulus, N = 11, P = 0.28, Wilcoxon signed rank test) and was comparable to electrically induced response of saline-treated cells at the same time point (4.8 ± 0.5 spikes/stimulus, N = 10, P = 0.45, U = 21.0, Mann–Whitney Wilcoxon test; Fig. 3b).
Reward location information departed from the baseline level 600 700 ms after the onset of texture information (Figure 5A).
In perfused rat hearts, the relative Ser23/24 phosphorylation level following 8-Br-cAMP treatment increased significantly from the baseline level (166.9±9.5% vs. 100±7.7%, n = 10 fibers from two rats; P<0.05).
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Hematology data indicated that WBC levels were significantly increased from the baseline levels by day 4 post-exposure (P = 0.0013), with the WBC levels in some dosage groups increasing above the normal range by day 10.
Conversely, binge-pattern EtOH exposure significantly increased CRH mRNA levels in EtOH pre-exposed animals compared to EtOH naive, however the levels were not statistically different from the baseline levels of EtOH pre-exposed animals (Fig. 2, solid bars).
The arthritic and control rats showed decreases in plasma pyridoxal 5'-phosphate from the baseline levels.
Moreover, the cytokine and NO levels in NAL after the vacation did not differ from the baseline levels taken before the challenges.
The cytokine and NO levels in NAL of samples taken after at least 1 week of vacation did not differ from the baseline levels before the exposures.
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