Sentence examples for from the basal side from inspiring English sources

The device also allows region-specific treatment of endothelium from the basal side, recreating organ-specific localization of signaling molecules produced by stromal cells in the extravascular space.

Using the microfluidic vasculature to selectively manipulate cancer cells and endothelium, we demonstrate that circulating breast cancer cells preferentially adhere to endothelium stimulated from the basal side with CXCL12.

The microfluidic vasculature produces spatially-restricted stimulation from the basal side of the endothelium that models both organ-specific localization and polarization of chemokines and many other signaling molecules under variable flow conditions.

We demonstrated similar results with CXCL12 by showing twice as much binding of CXCL12 and adhesion of 231-control cells onto endothelium stimulated from the basal side compared to apical (Figure 2).

We have described a compact, easily-fabricated microfluidic system to model serial interactions of circulating cancer cells with a vascular endothelium at defined sites stimulated extravascularly from the basal side by chemokines.

When added from the basal side, CXCL12 acts through receptor CXCR4 on endothelium to promote adhesion of circulating breast cancer cells, independent of CXCL12 receptors CXCR4 or CXCR7 on tumor cells.

Our optimized membrane, am-PSU1 (21.4% C O groups, 19.1% PVP-PSU; contact angle 71.5 80.80, PVP-PSU: 52.4 67.50), supports a confluent monolayer of RPTCs and prevents creatinine and inulin diffusion from the apical to the basal side, meeting the requirements for application in BAKs.

We could not find evidence that the small fraction of TCA-sensitive radioactivity, which was transcytosed from the apical to the basal side by CXCR7, contained biological activity.

At 37 °C, the entry of MWNTs-NH3+ into the PBEC monolayer occurred mostly via vesicular uptake with MWNTs-NH3+ clusters being transported from the apical to the basal side of the endothelial cell.

Cnn is highly enriched at the basal side from the apical (Crb) domain and AJ (E-cad) (Figure 3and, alsoalso basal and adjacent to the acetylated-microtubules (Figure 3B') [14] in the mid-pupal eyes.

The prostasin-reduced B6Tert-1 cells allowed the FITC-labeled dextran to pass through the paracellular space from the apical side to the basal side of the monolayer cells, as indicated by the higher intensity of fluorescence in the basal medium of these cells whereas the control cells essentially did not allow the FITC-dextran to pass through (Fig.  4e).