The striatum, on the other hand, showed long, wire-like, staining from 1 week onwards, subsequently changing to a more punctate form (Additional file 6: Figure S2b).
Ageing male DBA/1 mice spontaneously develop arthritis in the hind paws after grouped caging from the age of 12 weeks onwards [ 5, 7].
Arthritis characterized by ankylosing enthesitis is spontaneously occurring in aging male DBA/1 mice after grouped caging (> 4 males per cage) from the age of 14 weeks onwards.
Mice were treated daily with dexamethasone (0.5 mg/kg; Rotexmedica, Trittau, Germany) or phosphate buffered saline (PBS) by intraperitoneal injection from the age of 12 weeks onwards (n = 10 and 12 mice per group, respectively).
Despite this, our confidence intervals were of a reasonable width, and we were able to detect both the need for recalibration in SWS and an improvement in the area under the curve for pre-eclampsia from the addition of blood pressure measures from 28 weeks onwards in this cohort.
Expression of α8β1 increases dramatically during development of the smooth musculature from 16 weeks onwards (Beaulieu et al., 1993), including adult tissue (results not shown).
Label incorporation into acetylcarnitine was markedly reduced in the WD-fed animals from 4 weeks onwards providing early evidence of the effect of dietary composition on substrate metabolism and storage.
This is physiological for the placenta from 10 to 12 weeks onwards and will make results from different studies easier to interpret.
There were no differences between any of the WT groups except in the male handling groups, where the playground mice increased weight significantly compared to the home cage mice, from 22 weeks onwards (p = 0.027; Figure 9E).
In contrast, treatment with des-fluoro-sitagliptin and bezafibrate together significantly decreased blood glucose levels from 3 weeks onwards until the end of the experiment (Fig. 4a, b).
