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The results add to earlier findings in recent years from smaller studies in New Zealand and Australia.
Mr. Kindler suggested, however, that Pfizer could file for approval based on data from smaller studies that will be available next year.
The lead author, Dr. Casey Crump, a clinical assistant professor of medicine at Stanford, said the findings were consistent with those from smaller studies done in the United States.
Many sequences were associated with mental alertness, insulin regulation and DNA stability, confirming results from smaller studies and suggesting areas for life-prolonging research.The researchers also developed a statistical model to forecast longevity.
The MIT researchers, along with their collaborators at MGH and other hospitals, were interested in taking advantage of the vast numbers of patient scans, which would allow them to learn much more than can be gleaned from smaller studies that produce higher-quality scans.
The results of this study strongly confirm findings from smaller studies that the need for laparotomy during REVAR is associated with significantly worse 30-day survival.
Similar(14)
Evidence on unconventional risk factors is provocative but comes from small studies.
Those "preliminary results" necessary to acquire funding for new ideas used to come from small studies that emerged down unexpected byways while doing the primary research on a large grant-funded project.
Dr. Lauer cites another intriguing paper from the 1970s, by Amos Tversky and Daniel Kahneman, that highlights our biases when interpreting data, especially from small studies.
The available data from small studies show that in CHF conventional diuretics reduce the risk of death and worsening heart failure compared to placebo.
But studies so far are small, and results from small studies that seem too good to be true often are.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com