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In clinical trials, a covariate-adjusted response-adaptive (CARA) design allows a subject newly entering a trial a better chance of being allocated to a superior treatment regimen based on cumulative information from previous subjects, and adjusts the allocation according to individual covariate information.
This constant comparison between the responses in an ongoing interview with the responses from previous subjects allowed us to remain close to the concepts encountered while refraining us from adding our personal assumptions.
This is similar to the covariate-adjusted response-adaptive (CARA) designs investigated by Li-Xin Zhang and van der Laan, in which subjects who join a trial are allocated based on cumulative information from previous subjects, adjusted according to the individual's information [ 43, 44].
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Combined with results from lean to morbidly obese subjects (n = 39) from previous study, the collective data show a highly significant correlation between BAT activity and body composition (P<0.001), respectively explaining 64 % and 60 of the variance in BMI (r = 0.8; P<0.001) and BF% (r = 0.75; P<0.001).
One particular submission from a previous subject instance had phrasing that included "constructive employee execution" and "worker execution audits" for an assessment topic on employee performance reviews.
Silverman is not a music scholar, but rather a kind of biographical polymath, whose previous subjects have ranged from Cotton Mather to Harry Houdini.
His latest biographer, Fred Kaplan, whose previous subjects have ranged from Charles Dickens to Gore Vidal, argues that Adams doesn't fully deserve his reputation for coldness, but, for all its diligence, "John Quincy Adams: American Visionary" (Harper) never really succeeds in raising the sixth President's temperature.
Subjects were recruited through public notices and by word of mouth (subjects from previous studies, friends/associates of present and previous subjects).
To prevent confounding effects, replications occurred in areas visually separated from previous test subjects.
Previous subjects for the Women project have ranged from television host Ellen DeGeneres to artist Agnes Martin.
Previous subjects have included Jim Hodges and Lisa Yuskavage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com