Sentence examples for from point mutations from inspiring English sources

Exact(56)

First, it applies to all mutational events, from point mutations to gene duplications and deletions.

These animo acid substitutions result from point mutations at just two key positions in the structure of one protein component, the α3 subunit.

This disorder mainly results from point mutations, small insertion or deletions in the β-globin gene complex.

Strikingly, phenotypic alterations resulting from point mutations or deletions in the mbt repeats of the related Drosophila SCM protein are clustered in and around the ligand binding pocket.

Alpha1-antitrypsin deficiency results from point mutations that distort the structure of the protein to allow a unique protein protein interaction that we have termed loop-sheet polymerization.

This cell-active view of genome change applies to all scales of DNA sequence variation, from point mutations to large-scale genome rearrangements and whole genome duplications (WGDs).

The disappearance of the three-stranded antiparallel β-sheet is the last unfolding event, in agreement with a large repertoire of kinetic data derived from point mutations as well as glycine insertions and disulfide crosslinks.

This study demonstrates, for the first time in a large-scale validation, that rigorous free energy calculations can be used to predict changes in protein stability from point mutations without parameterization or system-specific customization, although further improvements should be possible with additional sampling and a better representation of the unfolded state of the protein.

that might also result from point mutations [27].

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Changes in protein domains result mostly from point mutations, insertion and deletion processes.

Cancer cells exhibit a wide range of genetic modifications, from point mutations to massive chromosomal aberrations (Stephens et al. 2011).

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