Exact(9)
The idea pursued is an 'in situ vaccination' to stimulate local and systemic anti-tumor immune response to treat established disease, and most importantly to induce immune memory to protect patients from outgrowth of metastasis and recurrence of the disease.
The occurrence of two highly similar but distinct lineages in WEAU could have resulted either from co-transmission of two closely related viruses, or from outgrowth of a random mutation that occurred in an early post-transmission replication [15]; while our data do not allow us to decide conclusively between these alternatives, several lines of reasoning argue for a single transmission.
Because the non-branching lines in our study also did not exhibit axillary bud initiation, we were unable to separate initiation from outgrowth and were thus unable to identify loci contributing specifically to one process or the other.
HDF obtained from outgrowth of explant cultures, were grown in DMEM (Dulbecco's modified Eagle's medium; Bio Whittaker) supplemented with 10% fetal calf serum (FCS), and cells from passages 4 to 8 were used.
Vaccination with Tc-ErbB2/Th-HA liposomes was even more effective, resulting in complete protection of all five mice in this group from outgrowth of Renca-lacZ/ErbB2 tumours.
Changes in the morphology and motility (assessed from outgrowth processes) of activated microglia were obvious in mice at 4 h post-CLP (10 min recording, Figure 1I, right panel), but were absent in the sham-operated mice.
Similar(51)
As the ductal type lesions encompass almost 80% of all diagnosed breast cancers6, ADH are derived from outgrowths of luminal epithelial cells and are morphologically related to low-grade DCIS.
The formation of the secondary palate from outgrowths of the maxillary prominences is a separate developmental process that occurs later, between E12-E15.5 of mouse embryogenesis [5].
In the author's laboratory, clonal mammary populations derived from outgrowths of individual mammary fragments from old, multiparous donors were created and carried through six transplant generations to growth senescence.
Therefore, muscle and bone tissues around the mandibular gingival tissues were carefully removed, and mGFs were obtained from the outgrowth of fibroblastic cells from the remaining tissues.
After insulin-transferrin-selenium (ITS) was added to the same medium only a single Grp94−/− ESC line was established among 10 ESC lines derived from 24 outgrowths from 30 blastocysts.
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