Sentence examples for from other regions of the tumour from inspiring English sources
In some tumours this region of maximal expression will not be visualised as the specimen cores will have been extracted from other regions of the tumour.
For example, a single sample from an individual tumour might reveal mutations which appear to be clonally dominant, but are then shown to be absent from other regions of the tumour (79– 81).
The most severe form of breast cancer occurs when the cancer spreads from the breast tissue to other regions of the body (metastasis), significantly increasing the tumour burden and often resulting in a fatal diagnosis.
Specifically, using array comparative genomic hybridisation and fluorescence in situ hybridisation, we have shown that INK4A/ARF is selectively deleted from >90% of tumour cell nuclei of supratentorial ependymomas but is rarely deleted from tumours arising in other regions of the CNS (Taylor et al, 2005).
Stage IV tumours have spread to other regions of the neck, the lymph nodes, or other organs in the body.
By a re-examination of biopsy 300 using sections from other parts of the tumour, we found that the tumour did in fact contain tumour-infiltrating lymphocytes that also extended into the non-neoplastic regions.
In 81 tumours multiple analyses were performed from different regions of the tumour, ploidy discrepancy was seen within the same tumour in 13/81 tumours (16%), and intra-tumour variation in proliferative index (PI) in 72 tumours was estimated at +/- 5%.
The darkest staining intensity was consistently seen adjacent to necrotic regions, but there were also other regions of dark staining unassociated with necrosis within tumour sections.
