Exact(2)
Most of the synthesized compounds showed from moderate to potent activities against c-Kit with IC50 values in the nanomolar range.
All new compounds showed from moderate to potent activities against wild-type (wt) BCR ABL1 kinase with an IC50 range from 14.2 to 326.0 nM.
Similar(58)
The strength of association varied from moderate to strong.
A large number of moderate to potent tyrosinase inhibitors from natural and synthetic resources have been reported during the last decade 5 9.
Most of these new compounds showed moderate to potent activities against wild-type HIV-1 with an EC50 ranging from 4.48 μM to 0.18 μM.
The results of initial screening showed that 500 mg/L of the newly synthesized compounds have moderate to potent activities.
Most of the target compounds displayed moderate to potent antiproliferative activities.
Most compounds showed moderate to potent cytotoxic activities against the tested cell lines.
Majority of the synthesized compounds exhibited moderate to potent activity against MGC-803 and MCF-7.
Most compounds exhibited moderate to potent inhibitory activities against both CDK2/cyclin A and CDK9/cyclin T1 systems.
Most of these synthesized compounds exhibited moderate to potent antagonistic activities in CREs driven luciferase assay.
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