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Most of the data on the benefits of statin use come from larger studies that looked at adults of varying ages.
The Ghanaian study echoed one conclusion drawn from larger studies in the United States and New Zealand, Dr. O'Brien said: that apnea in pregnant women raises blood pressure and increases risk to the baby.
The possible association of CTP parameters with clinical tumor stage also needs confirmation from larger studies.
Conclusion: The outcomes for this patient population compare favorably with previously published survival data from larger studies.
When that time comes, says Sahakian, developing laws and policies that deal with the ethical challenges, and allow individuals to balance potential benefits and costs will be much easier if we have data from larger studies into the effects of these drugs.
Small studies may have been published preferentially when they show significant results while the evidence from larger studies may be available regardless of the results.
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Results of this study need further validation from larger study.
The agency usually makes such choices after years of deliberating over findings from large studies.
Neither of these ideas has been supported by evidence from large studies.
Still, the harms like an increased risk of prostate cancer or heart attack would emerge only from large studies, for example the federal study of estrogen in women, which followed thousands of participants for years.
Findings from large studies of some prevention methods, like the use of microbicides and male circumcision, are expected within the next five years, some possibly in about a year, the panel said at the 16th International Conference on AIDS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com