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The intervention would benefit from further trialling and refinement and could be made available to other groups such as women living with HIV, the wives of IDUs, and specific sub-groups of widows such as sex workers and IDUs.
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Results from further trials are expected in 2016, but the drug is unlikely to be available on the NHS for quite some time.
Evidence from further trials, including trials using oxaliplatin/capecitabine combinations may help to clarify these issues.
However, results from further trials in different populations are urgently needed to extend the evidence base.
Thus, more information will have to be obtained from further trials or soon become available from registries.
One patient was erroneously excluded from further trial participation by an investigator; no patient was lost to follow-up.
If a participant withdraws consent from further trial participation their data will remain on file and will be included in the final study analysis.
Patients were withdrawn from further trial treatment if treatment was delayed by more than 3 weeks due to haematological toxicity or if they experienced any grade IV non-haematological toxicity.
Beta error: the accepted probability of rejecting from further trials a regimen with a true CR/CRi rate at least equal to P1 and a true toxicity rate equal to or lower than (1-T1).
If a participant withdraws consent from further trial participation (please note that this would be different from withdrawing from the study intervention), no further assessments will be conducted but their data already collected will remain on file and be included in the final study analysis (unless the participant has specifically requested for their data to be destroyed).
IFAB, which sees the four home nations and Fifa come together to discuss the laws of the game, recommended that two versions of goal-line technology be put forward for further trials - one from British company HawEye and the other a German-Danish system called GoalRef.
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CEO of Professional Science Editing for Scientists @ prosciediting.com