The paper divides the ISR into four logical phases: setting a computational architectural diagram for each phase, proceeding from functional perspectives (input, process, and output), and their consequences.
Reviewer #1: The challenge of interneuronal heterogeneity is immense, and a recent review by Kepecs and Fishell (2014) suggests that we need to consider interneuron diversity from functional perspectives (behaviour or network dynamics), rather than simply classification.
The designed system architecture is modular from the functional perspective and hierarchical from the technical point of view.
From a functional perspective, transfer of electrons from Fdx has been shown, albeit indirectly, and in a dithionite (DT) dependent manner [17].
We have shown that either from a quantitative point of view or from a functional perspective there are no systemic differences influencing the evolution of proximal promoters and proteins.
The structural assignment of the toxin nucleoside linkage, however, is less critical from a functional perspective, as multiple reaction products are bound to result from brevetoxin reactive intermediates.
From a functional perspective it is not the activity training per se, but rather its function, that is interesting.
From a functional perspective, the lingering question is why diverse copies of CAD genes from Class II and Class III have been maintained within plant genomes.
The name "novel genes" would be justified because the exceptionally fast rates in their initial stages, just after the duplication, made them unrecognizable from the sequence point of view and determine their point of birth from a functional perspective.
From a functional perspective, clans help to unify groups by cross-cutting other forms of social organization, such as the settlement, postmarital residence patterns, or age sets.
