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Genomic DNA from each line was extracted using the DNeasy Plant Mini kit (Qiagen, Germany).

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Total RNAs from each cell line was extracted using RNAiso Plus (TAKARA, Japan), and examined Qubit fluorometer (Invitrogen, Thermo Fisher Scientific, USA).

Genomic DNA from cell lines was extracted using a genomic extraction kit (Sigma).

RNA from cell lines was extracted using the Trizol protocol (see above).

Total RNA from cell lines was extracted using TRIzol (Invitrogen), as previously described.

Briefly, total RNA from neuroblastoma lines was extracted using the RNAeasy kit (Qiagen, Valencia, CA).

Total RNA from cell lines was extracted using a commercial kit (Amersham Bioscience-GE HeAmersham Bioscience-GE

Genomic DNA from the hESC lines was extracted using DNeasy kit (Qiagene).

Total RNA from cultured cell lines was extracted using the cesium-chloride method.

The total RNA from breast cell lines was extracted using the RNeasy kit.

Total RNA from CAL51 cell lines was extracted using Trizol (Invitrogen) according to manufacturer's instructions.

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