Assume a population of 109 organisms; 200 of these acquire a gene from a divergent organisms.
This finding is somewhat surprising since antifreeze proteins from phylogenetically divergent organisms (insects, fish, plants, etc.,) generally have very little similarity to each other [ 71].
High sequence conservation in proteins from widely divergent organisms is an indication of extreme "purifying" selection; relatively few sequence changes have been tolerated over billions of years.
This glutamate is conserved in acetate kinase sequences from widely divergent organisms and is also present in the C. acetobutylicum AK (Singh-Wissmann et al. 1998).
This analysis exemplifies the value of our method for the reliable discovery of code variants, even in fragmented DNA from taxonomically divergent organisms.
This association, however, is difficult to reconcile with the perceived degree of sequence conservation between the homeodomains of Hox genes and the numerous examples of functional equivalence of Hox/Hom genes from strikingly divergent organisms [ 24- 28].
Because similarities in sequences from highly divergent organisms often imply functional constraints, the CNEs we identified, especially those in the "gnathostome" group, were most likely indicative of potential important functional elements.
Kinobeads consist of immobilized analogues of a variety of ATP competitive kinase inhibitors that show relatively promiscuous binding to the mammalian kinases, but their ability to bind kinases from more divergent organisms has not been examined.
The results also provide insights about how the enzymatically conserved Gcn5 protein is utilized divergently in evolutionarily divergent organisms.
The ribosomal scaffold will tell us about the central tendency of the ribosome, after removing transfers between divergent organisms (such as described in [ 94] ) from the averaging.
