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Advancing a drug from discovery of a therapeutic target to human trials and commercialization.
(Continuation of 240A) Advancing a drug from discovery of a therapeutic target to human trials and commercialization.
A span of about 100 years marked the period from discovery of furfural in the laboratory to the first commercial production in 1922.
After 200 years from discovery of hydrogen peroxide by Thenard, we now use synthetic biology principles to study functions of H2O2 in biological systems.
And it takes even more (the industry standard is $800 million from discovery of a molecule to FDA approval) to guide the hundreds of other compounds that are in earlier phases of trials through to the approval finish line.
In order to characterize A/H5N1 viral sequences, a bioinformatics approach accurately identified viral sequences from discovery of a sequence signature, which provided enough distinctive information for sequence identification.
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I will then describe the dramatic gains in sensitivity that are expected from discoveries of millisecond pulsars, more sensitive instrumentation, improved detection algorithms, and international collaboration and show that detection is possible before the end of the decade.
In part, that's come from the "discovery" of Alamos by expats from across the globe, including a hefty number from the U.S. and Canada.
The symphony's inexhaustible novelty comes not from the discovery of new sounds — although there are many — but from the diabolical manipulation of familiar ones.
One of the weapons possession charges stems from the discovery of a pistol in the vehicle.
North Dakota has benefited from the discovery of the Bakken Shale, an oil-rich deposit.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com