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(Many drugs, from aspirin to opiates, derive from compounds designed by plants).
Most antibiotics came from compounds made by micro-organisms in the soil.
Crowded coasts face a bigger threat from compounds containing nitrogen and phosphorus.
But the remaining 29% are manmade, and about 49% of those come from compounds commonly used to remove snow and ice from roadways.
It also warns of potential toxic effects on humans and animals from compounds such as bisphenol A and nonylphenol, used in plastic manufacture.
Lexicon's pharmaceuticals division is looking for new drugs using this method.The enthusiasm for combinatorial chemistry also diverted attention away from compounds derived from natural products.
Pheromones, for example, are usually derived from compounds that are natural breakdown products of body metabolism, such as the compounds in urine.
In 2007, 139 such vehicles were hijacked or stolen from compounds and 77 relief convoys looted; 147 aid workers were temporarily abducted.
Whether the resulting markings on Jupiter arose from the original cometary material or from compounds synthesized in the impact explosions was still hotly debated.
American military officials say their two investigations show that Taliban fighters had deliberately fired on American forces and aircraft from compounds and other places where they knew Afghan civilians had sought shelter, in order to draw an American response that would kill civilians, including women and children.
The successful production of a useful fibre by chemical synthesis from compounds readily available from air, water, and coal or petroleum stimulated expansion of research on polymers, leading to a rapidly proliferating family of synthetics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com