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It presents also a brain-specific isoform deriving from an alternative splicing and containing 41 additional N-terminal amino acids.
The approach is particularly valuable while making inferences in isoform identifications from an alternative splicing database.
SpA patients exhibit high levels of circulating sCTLA-4 that may result from an alternative splicing of CTLA-4 transcripts.
GHS-R has two variants of splicing: functional type 1a and truncated type 1b, which arises from an alternative splicing and its function is still unclear [ 2, 3].
A soluble form of CTLA-4 (sCTLA-4), resulting from an alternative splicing, has been identified and was found increased in several autoimmune diseases.
In bovine, pig and human, the mRNA expression observed in the testis results from an alternative splicing of the ZAR1 gene [ 11].
Similar(46)
But unlike human SLC11A2, where the differences in the 3' end result from alternate exon usage [ 63], in sea bass the differences result from an alternative splice site in exon 15.
The 8 amino acid discrepancy in length results not from the substitution of exon 15 for exon 16, but rather from an alternative splice site in exon 15.
HLA-G proteins can be expressed as seven distinct isoforms, by means of an alternative splicing from a single primary transcript.
This suggests that applications of multiple search engines effectively reduced the possible false positive results and validated the protein identifications from tandem mass spectra using an alternative splicing database.
Another advantage is that where the transcript assembly indicates that there is an alternative splicing, prediction from transcripts allows the coding sequences splicing alternatives to be predicted.
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