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Finally, weakly aligning regions were trimmed from alignments using trimAl (Capella-Gutiérrez et al. 2009) with the following parameters: -gt 0.1.

Family classification is derived primarily from alignments of the sequences of the core motor domain.

We follow the procedure in [3] with training starting from alignments and lattices generated using the cross-entropy-trained DNN.

Trees derived from alignments of full-length sequences, conserved 'core domain' hydrophobic region sequences, and α2-repeat region sequences.

We thus excluded the recombinant haplotypes from alignments of BS05 × BS17 that were shared with BS05 or BS17.

Understanding the link between structure and function is critical to improving enzyme design and the prediction of protein function from structure without transfer of annotation from alignments.

To detect the evolutionary relationships of GLRs, a phylogenetic tree was generated from alignments of 13 OsGLRs in rice and 20 AtGLRs in Arabidopsis (Fig. 4 and Additional file 5).

The similarity scores calculated from alignments supported the phylogenetic results.

Nearly all homeodomain phylogenies that have been published recently are derived from alignments of amino acid sequences.

Prior to analysis, alignments were performed with Clustalw [30] and gaps and ambiguous characters were removed from alignments.

Distance dendrograms were constructed from alignments of nucleotide sequences or predicted amino-acid sequences of putative mature proteins translated from the open reading frames (Figure 1).

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