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Capitalizing on crystal structure information obtained from a previous effort in the search for non peptide inhibitors of the p53 MDM2 interaction, we have discovered another new class of compounds able to disrupt this protein protein interaction, an important target in oncology drug research.
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Differently from these previous efforts, in the present work we focus on analyzing strategies for designing and managing distributed applications onto human computation platforms.
This model development parallels previous efforts in the fundamental modelling of the PAFC cathode.
The statement from Mr. Immelt in the annual report recalls a previous effort by a G.E. chairman to deflect rumors that the company intended to sell NBC.
In a previous effort, total least square regression (TLSR) was exploited as a method for estimating the connection coefficients r i j from noisy perturbation responses [ 16].
BTB builds upon the successes and lessons learned from prior depression treatment efforts but it also differs from previous efforts in important ways.
In short, companies in the industrialized world were unjustly enriching themselves by profiting from previous efforts made in the developing country.
Previous efforts in EST sequencing from this species revealed a high level of sequencing redundancy, largely due to very high proportion of mitochondrial genes [ 12, 17].
Previous efforts in NSW, Queensland, South Africa and Hawaii only passingly inform it.
But previous efforts in Pinzón have been unsuccessful.
This demonstration also looks set to be bigger than previous efforts in Dover.
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