Since the candidates we considered spoke some 265,472 words across all of their appearances, a computational solution is preferable.
We thus developed a computational solution that leverages multidimensional scaling (MDS) to assess stage similarities on a transcriptome-wide scale.
BS-Seeker2 provides a computational solution to remove reads with incomplete bisulfite conversion (Additional file 1: Supplementary Methods).
The solution accuracy is shown to be greatly improved for the driven cavity problem when the analytical solution of the singular flow behavior in the upper corners is separated from the computational solution.
An effective lattice theory enables an efficient computational solution to an otherwise intractable problem.
ExprTarget is inspired by a multivariate logistic regression model for a binary outcome and predictor variables from existing computational solutions.
Finally, the prediction results of our integrative approach are provided through an online searchable database, ExprTargetDB, which can also be used to compare the prediction results (i.e., p values, scores) from the various computational solutions we tested in this study (i.e, miRanda [25], [26], PicTar [30], TargetScan [27] [29], TarBase [23], [24], and our LCL data).
On the other hand, from a computational point of view, GNA is arguably more difficult than LNA since it must find a solution among all possible global matchings.
Results provided from a computational experiment over common benchmarks showed which parameters and genetic operators affect the quality of provided solutions.
In accordance with the theoretical analysis, a two-stage solution is also proposed to resample propagated particles that are suitable for invoking KBOT from a computational perspective.
