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Fringe modifies the receptor Notch and makes D cells more sensitive to Delta and less sensitive to Serrate [31], [32].
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The experiments revealed that Fringe proteins modify specific same-cell interactions in a way that enables a cell to receive one type of Notch signal from a neighboring cell and send a different type of Notch signal to another cell at the same time.
Lunatic Fringe (Lfng) can modify the glycosylation pattern of Notch1 receptors (but not Notch2) in a manner that potentiates DLL1-mediated signaling but inhibits Jag1-mediated signaling [71], [72], [73].
Instead, Notch ligand choice is modulated by other proteins such as Fringe and O-fucosyltransferase that modify Notch EGF residues [ 110].
The glycosylation status of the Notch receptor is modified by Fringe proteins (radical, maniac and lunatic), and these post-translational modifications are important for ligand binding.
The modified, or incoherent, fringe projection technique is based on a Michelson interferometer set up in which an incoherent extended light source is used to project straight Fizeau fringes directly onto the retina.
The following steps comprise the process of a modified stair phase-coding fringe.
A modified stair phase-coding fringe was designed, and a new phase unwrapping algorithm based on stair phase-coding fringe was presented.
In this paper, a modified stair phase-coding fringe is designed, and a new phase unwrapping algorithm based on shifting fringe order is presented.
First, basing from Zhou's method [19] shown in Fig. 1a, we design a modified stair phase-coding fringe that exactly retrieves the codewords.
Fringe proteins are also known to modify the DSL ligands (Panin et al., 2002); however, a functional role for sugar modifications of the DSL ligands has not been forthcoming (Muller et al., 2014).
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