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The PHQ-2 has not been as frequently validated as the PHQ-9.
Therefore, the measured value should be frequently validated by relaxation verifications.
The GAD-2 has not been as frequently validated as the GAD-7.
Our results also sound a cautionary note that RNAi status should be frequently validated in the studies involving apoptosis and that while stable RNAi can be safely used for the study of early apoptotic events, transient RNAi is more suitable for the study of both early and late apoptotic events.
Case-finding algorithms (56.7%) were more frequently validated than diagnoses codes alone (37.8%).
The most frequently validated score is the Finnish Diabetes Risk Score, validated in 8 independent cohorts (51, 55, 64– 64).
Surprisingly, even the more-common models developed some 25 years ago have not been frequently validated in an older subgroup.
One model with biochemical measures that has been frequently validated in independent populations is the San Antonio Heart Study model (50).
Information from birth certificates is considered a criterion standard because it is nearly universal, includes self-reported race and ethnicity, and has been frequently validated [ 16- 19].
Derivatives of the model output with respect to changes in input, known as local sensitivities, are frequently validated experimentally or used to predict potential targets for pharmaceuticals [ 2].
Citation analysis of the individual scales showed that the Anticholinergic Cognitive Burden (ACB) scale was the most frequently validated expert based anticholinergic scale for adverse outcomes (N = 13).
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