Arginine is the most frequently substituted residue in both datasets (AASs and harmful AASs) while the substitutions from alanine and glutamate are less frequent among harmful AASs (Additional file 5: Figures S5 and S6).
Grinnell frequently substitutes in three waves of five -- like hockey shifts.
At the beginning of the colonial period, stamped metal foundry pieces frequently substituted for scarce currency.
During this period, lights exhibited from chapels and churches on the coast frequently substituted for lighthouses proper, particularly in Great Britain.
One of the things for which I will never forgive the last Labour government was its devotion to vocational training, frequently substituting that for proper academic subjects.
Variscite is cut en cabochon (with a round, convex, polished surface) for brooches, earrings, and beads and is frequently substituted for turquoise.
The short routes Marino cited are frequently substitutes for running plays, and as the N.F.L. shifts division games to late in the season to ensure competitiveness, quarterbacks are unlikely to get as much rest as they have in the past.
But scholars and civil rights groups said that the case represented the problems with a judicial system where witness testimony, often coerced, frequently substitutes for physical evidence and adequate investigation.
Bell made headlines by quitting several high-profile jobs on the grounds of ethical protest, and he provoked both criticism and praise from his peers by frequently substituting parables and allegories for traditional analysis in his legal writings.
Studies have frequently substituted distress-related constructs (e.g., self-esteem and general well-being) for measures of internalizing mental health problems.
