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The majority of ICU survivors experience immediate and frequently persistent physical, mental and cognitive impairments that compose post-intensive care syndrome (PICS) [1 3].
Nasal obstruction was the symptom most frequently persistent despite immunotherapy and the one most frequently reported to be improved by surgery.
Lifetime prevalence of depression is high [ 2] and depressive episodes are frequently persistent and recurrent [ 3].
These symptoms are 'common, frequently persistent and are associated with significant distress, disability and unnecessary expenditure of medical resources' [ 4].
Another feature of developmental immunotoxicity is that alterations after early exposure are frequently persistent and last long after exposure, frequently into adulthood of the exposed offspring.
For almost all women, the frequently persistent psychological morbidity will be accompanied by need for surgery, radiotherapy and some form of adjuvant medical treatment.
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Viral infections that were cleared months or years earlier are not likely to account for the IFN signature in SS because the immune response returns to normal after viral clearance, and persistent viruses frequently "persist" because they do not induce strong IFN responses.
Students' misconceptions regarding natural selection are frequently so persistent that students may be unprepared for the human evolution question unless instructors have previously addressed common student misconceptions regarding inheritance.
Ehrlichiae frequently cause persistent infection in their natural hosts, which appear to utilize immune defense mechanisms against species-specific ehrlichia strains.
Carcinoma cells are frequently under persistent oxidative stress.
Carcinoma cells in vitro and in vivo are frequently under persistent oxidative stress.
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