The most frequently observed reasons for prominent intra-individual polymorphism of nrDNA are hybrid/allopolyploid origin [ 27, 28, 30, 32, 33, 61, 62] or the occurrence of pseudogenes [ 63- 67].
The most frequently observed reasons for non-adherence were the presence of active disease according to the rheumatologist (that is, based on the presentation of the patient's overall disease activity, in particular, the degree of arthritis) and drug side effects.
A late summer and early autumn peak of cryptosporidiosis are frequently observed in annual reports although reasons for this observation are not entirely clear [ 10].
At specialized pediatric gastroenterology clinics, fecal incontinence is frequently observed and may be the reason for referral to the specialist.
The staff will be unaware of the reason for the observations; they are already frequently observed for training or research purposes.
We speculated that one reason is migraine was less frequently observed as the first clinical manifestation in Chinese CADASIL patients than in Caucasian patients, who usually showed the symptom as early as 30 years old [1, 9].
This is not a trend frequently observed in the region [ 7] and the reasons motivating it should be explored further.
A reason is also offered for the frequently observed difference between the crystallinity determined by the density and that obtained by the enthalpy of melting.
