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The language barrier is frequently mediated through the use of a translator or interpreter.
Cellular regulation, at the level of both signalling and gene expression, is frequently mediated by proteins whose activity changes over time, often in a pulsatile manner.
Bacterial infection induces apoptosis which is frequently mediated by the direct activation of caspases in the absence of death receptor ligation.
Protein protein recognition, frequently mediated by members of large families of interaction domains, is one of the cornerstones of biological function.
The switch between mutually exclusive OFF to ON state in response to a stimulus is frequently mediated by a control circuit with a positive and/or a negative feedback.
In eukaryotic cells, nuclear export of proteins is frequently mediated by this nuclear export factor, which binds to nuclear export signals (NES) on cargo molecules.
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RGD tripeptide motifs frequently mediate ligand binding to integrins.
When examining whether miRNA seeds in different locations of coding region have different synergistic effect, we found that seeds residing very close to the stop codon frequently mediate very strong effects (two times more than the average effect) on mRNA levels in most experiments (eight/ten) (Figure S2).
Thus, data from both neuronal and tumour cell systems converge on the view that laminin-binding integrins frequently mediate distinct cell behaviours typified by rapid migration, smaller focal complexes, and fewer actin stress fibres.
As surface components frequently mediate specific interactions of a pathogen with its host organism, especially S-layers of pathogenic strains are expected to have an important role in virulence (see also section 'S-Layers related to pathogenicity').
These are powerful regulatory enzymes that control the polarity and migration of individual cells as well as the development of multi-cellular structures, (Suzuki et al, 2003) frequently mediating opposing effects on homoeostatic regulators and mechanisms such as ion channels (Muscella et al, 2005).
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