Thanks to the proposed MSSR algorithm, our framework is immune to the changes of iso-value, transfer function and view parameters, which is especially efficient in scenarios requiring frequently interactions.
This study presents and investigates several frequently occurring interaction patterns for atomic-level protein-ligand interactions.
We present several frequently occurring interaction patterns, defined in terms of prevalent interactions between specific atoms of specific residue in the protein's pocket and specific atoms of the ligand, for the abovementioned four groups and for the specific types of interaction forces.
Coiled-coils were traditionally viewed as rod-like spacers separating functional domains; however, growing evidence suggests that they frequently contain interaction sites and act as protein effectors or scaffolds enabling protein protein interactions (Zhang et al. 2009; Munro 2011).
From our previous study with iPCA [6], only important and frequently used interaction features were replicated as touchable buttons in iPCA-CE.
We summarize and analyze 10 frequently occurring interaction patterns that cover 56% of all considered complexes and we show a practical application for the patterns that concerns interactions with organic compounds.
This most frequently identified interaction form is passed onto the verification component.
Systems biology papers frequently contain "interaction maps" for cellular or biochemical processes, as defined in a number of studies (see for example [ 16, 61]) based on the formalism of Molecular Interaction Maps http://discover.nci.nih.gov/mim.
The Top-10 Lists from every dataset are passed onto Evidence merger, which searches for the most frequently appeared interaction form in the Top-10 Lists of a target gene.
The methodology is viable in other contexts where computer applications change frequently, immediate interaction is desired, complex technologies are to be learned, and there is a need to monitor student work in real time.
