Due to the progressive nature of T2DM, multiple agents addressing different, yet complementary, mechanisms of action are frequently needed to achieve individualized glycemic goals.
Nutritional requirements should be individualized and frequently reassessed to avoid under- or overfeeding, azotemia, hyperglycemia, hypertriglyceridemia, electrolyte and acid-base imbalance, and fluid overload [ 85].
Thus, a clinical method to screen patient candidates for AAV-specific NAbs prior to treatment, especially with the frequently used AAV8 capsid component, will facilitate individualized treatment design and enhance therapeutic efficacy.
As standard QTc methods, such as Fridericia, Bazett and individualized corrections derived from resting ECGs, are frequently inappropriate for QT assessment during significant heart rate increases, a two stage procedure was implemented to determine the most appropriate heart rate correction method prior to QTc analysis [ 17].
The frequency should be individualized although DEXA should not be performed more frequently than every 6 months.
23, 24 Thus, to maintain positive therapeutic effects, the Summary of Product Characteristics (SmPC) states that treatment should occur no more frequently than every 3 months at a standard dose of 20 U. 1 In practice, however, doses and treatment intervals are individualized based on factors such as sex, muscle mass, and physician or patient preference.
"Education should be individualized.
But each is individualized.
Players require individualized treatment.
