Clinicians frequently find it difficult to manage sarcoidosis patients due to the significant variability in disease manifestation, diverse organ involvement and multiple non-specific symptoms.
In the period leading up to an acute admission, the person with dementia frequently became more difficult to manage because of disorientation, challenging behaviours and reduced physical function.
Interestingly, the symptoms that GPs most frequently indicated to be most difficult to manage were also those they most frequently indicated as most distressing of all physical and psychological symptoms ie shortness of breath, lack of energy and pain.
This may support the fact that this frequently-relapsing population is difficult to manage and has poor adherence to medication.
Though closed treatment has proven to be successful, a long-leg cast is difficult to manage and patients frequently experience long-term loss of joint range of motion [10].
The agency has long complained that these disconnected checkerboard properties are difficult to manage, and it has frequently used land exchanges to consolidate its holdings.
Unilocular cysts are probably the most difficult to manage because they are frequently small and consist of a broad spectrum of benign to potentially malignant pathologies, including pseudocyst, MCN, IPMN, and SC.
Infections due to Staphylococcus aureus associated with foreign implants, such as orthopaedic prostheses and intravascular devices, are very difficult to manage by antimicrobial therapy alone and frequently require the removal of infected materials [ 1].
