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The cancer resistant phenotype can be retained for life if the mice are frequently challenged with cancer cells.
Prophylaxis, the prevention of infection in uninfected people, is most beneficial under high transmission conditions when individuals are frequently challenged with infectious bites.
Within a plant tissue or organ, cells are frequently challenged with limited levels of oxygen supply due to changes in the external environment or high rates of cellular metabolism [ 10, 11].
Photosynthetic organisms that support much of the life on Earth, in using solar energy to renew the oxygenic atmosphere and make up organic assimilates essential to the food chain [ 1, 2] are frequently challenged with toxic reactive oxygen species (ROS) generated by respiration and photosynthesis [ 3], and toxic metals that constitute persistent pollutants because they cannot be degraded.
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However, the novel has also been controversial with parents; it ranked in fifth place on the American Library Association's list of frequently challenged books for 2010, with "unsuited to age group" and "violence" being among the reasons cited.
Channel 4 delivered with an iconoclastic commissioning strategy that sometimes shocked, often entertained and frequently challenged.
He was frequently challenged.
National Library Week is here again, which brings with it the American Library Association's annual state-of-the-industry report, as well as the list of the most frequently challenged books.
Thus, researchers are frequently challenged as to guidelines and practice.
Health care systems are frequently challenged by issues of access, continuity, fragmentation and quality of care in addressing the needs of older persons with chronic illness [ 1].
He bucked his country's intellectual fashions at times, condemning oppression under the populist revolutionary government of Gamal Abdel Nasser, praising his successor, Anwar Sadat, for seeking peace with Israel, and frequently challenging received pieties, including those of Islam.
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