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MEMo automatically identifies mutually exclusive alterations targeting frequently altered genes that are likely to belong to the same pathway.
The shapes of oma designs are frequently altered by Cecil Balmond, a Sri Lankan engineer at Ove Arup, a London firm.
(because long-term memory is frequently altered in delirium) [20].
CDKN2A was the next most frequently altered gene with >20% of patients carrying copy number losses.
The wnt signaling pathway was found to be the most frequently altered in HCC.
The frequently altered genes and pathways in HCC reflect classical cancer hallmarks.
The phosphoinositide 3-kinase (PI3K) pathway is one of the most frequently altered signaling pathways in human cancers.
G proteins and GPCRs are frequently altered in human cancers (Kan et al., 2010; O'Hayre et al., 2013).
Cell morphology is frequently altered in cancer cells, which are phenotypically categorized based largely upon morphological characteristics.
In contrast, the expression levels of isomiR-5p and isomiR-53p are less frequently altered after TDP-43 knockdown.
The phosphatidylinositol 3 kinase (PI3K) signalling pathway is frequently altered in human cancer and a promising therapeutic target.
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CEO of Professional Science Editing for Scientists @ prosciediting.com