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Because non-conserved miRNAs frequently accumulate at a lower level than conserved miRNAs, traditional small-scale sequencing often misses the specific-miRNA, the same as most comparative methodologies, particularly when the miRNAs are evolving rapidly [12].
Many mammalian proteins can be expressed at high levels in the prokaryotic host E. coli, but frequently accumulate in a misfolded and biologically inactive form in inclusion bodies [1].
Thus, new combinations of virulence genes can result in new pathogenic strategies, and such combinations frequently accumulate in pathogenicity islands.
As mentioned previously, plants frequently accumulate WSC in the leaves and stems at the vegetative stage, and these WSC are converted to lactic acid during silage fermentation [ 5].
Although fzl mutant plants are not deficient in thylakoid formation per se, fzl chloroplasts are large and unusually shaped, they contain abnormal proportions of stromal and granal lamellae and they frequently accumulate small vesicles (Gao et al, 2006).
Hot spot archipelagoes, in particular, are fecund cladogenic settings, and these chronologically arrayed island chains frequently accumulate species-rich endemic radiations that are of exceptional interest to evolutionary biologists [ 2- 4].
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Since then, the company has frequently accumulated large arrears to oil companies, airports, the tax department and its employees.
These pellets are frequently accumulated around the nest or roost sites, which can be used for years, even centuries.
The snail hepatopancreas proved to be extremely sensitive to HM traces from soil and have frequently accumulated several times higher amounts of Cu, Zn, and Cd than in lower trophic levels (soil and nettle); therefore, this organ can be used for tracking HM bioavailability in soil.
The Ci protein was frequently accumulated in CSN5 or Nedd8 MARCM clones (Figure 7C, E), while it was virtually undetectable in adjacent non-mutant neurons.
This investigation of the possible detection of PrPres by Western blot in the spleens of TgOvPrP4 ovine transgenic mice infected with an extended panel of ruminant TSE sources, confirms that PrPres frequently accumulates in the spleen of TgOvPrP4 mice infected by intra-cerebral route and extends our earlier observations [20].
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