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After the INDEL region, 15 of the next 20 nucleotide sites exhibited very frequent substitution.
The next most frequent substitution event observed was 2 consecutive base substitutions.
FAP results from mutation of the transthyretin gene, with Val30Met being the most frequent substitution.
The most frequent substitution was AUN (Ile) to GUN (Val) (62 sites), and the next was ACN (Thr) to GCN (Ala) (40 sites).
The two most frequent substitution patterns in SLS were "knee medial to the supporting foot" and "displacement of trunk" (both present in 9/16 participants).
Further, Gly to Arg, Arg to His, and Arg to Gln were the three most frequent substitution mutations in aaRSs (Tables 1 and 4).
Similar(49)
Thermostable proteins of Thermus organisms were characterized with a greater number of alanine residues accumulated by replacing serine, threonine and glutamate with this amino acid; frequent substitutions of isoleucine to leucine and valine; accumulation of arginine by substituting lysine and glutamine; and a decreased frequency of aspartate substituted by glutamate.
The frequent substitutions that result are often cited as a major annoyance of these services.
The aforementioned positions include indeed the most frequent substitutions associated with ESBL-production phenotype (Cohen Stuart et al. 2010).
The most frequent substitutions are C-to-T (26.6%) and G-to-A (25.4%; Figure 4 small RNA sequencing data (Ebhardt et al.2009), which is similar to the results obtained by using the rice and Arabidopsis.
Relatively frequent substitutions in group [M-C] tend to have long distances between amino acids, whereas relatively frequent substitutions in group [S-C] tend to have short distances between two amino acids.
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