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Despite the frequent resistance to quantitative analysis in some corners of the humanities, Mr. Pinker said he was confident that the use of this and similar tools would "become universal".
WASHINGTON — Nine years after the United States vowed to shut down the money pipeline that finances terrorism, senior Obama administration officials say they believe that many millions of dollars are flowing largely unimpeded to extremist groups worldwide, and they have grown frustrated by frequent resistance from allies in the Middle East, according to secret diplomatic dispatches.
Chronic headaches represent a challenge for physicians, given their frequent resistance to therapies, risk of relapse and associated comorbidities.
In this study and in other studies, the most frequent resistance phenotype was that of streptomycin for Escherichia coli, Klebsiella pneumonia, and Proteus species [29].
H274Y (the most frequent resistance mutation in human influenza A) was seen in four isolates in N1 and one isolate in N2.
A major problem in finding treatments is the frequent resistance to drugs which emerges.
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The most frequent resistances of MRSH isolates was demonstrated to benzylpenicillin (91.7%), erythromycin (91.7%), gentamicin (75.0%), tetracycline (66.7%), fluoroquinolones (41.7%) and co-trimoxazole (41.7%).
The most frequent resistances of MRSH isolates demonstrated were to benzylpenicillin (91.7%) with the presence of the blaZ gene; erythromycin (91.7%) and clindamycin (41.7%) with the presence of ermA, ermC, and msrA genes; and gentamicin (75.0%) with the presence of aac(6′ -Ie-aph(2")-Ia and aph(3′)-IIIa genes.
In the most frequent drug resistance profile, the resistance proteins P-glycoprotein/MDR1 (MDR1, ABCB1), thymidylate-synthetase, glutathione-S-transferase-π, metallothionein, O-methylguanine-DNA-methyltransferase and major vault protein/lung resistance-related protein were up-regulated.
In the most frequent drug resistance profile (cluster 4) all resistance proteins investigated (MDR1, TYMS, GSTP1, MT, MGMT, MVP/LRP) were up-regulated.
In STEC strains, the most frequent drug-resistance combination was resistance to ampicillin, cefalothin, and tetracycline, which was detected in 8 isolates, once with resistance to amoxicillin/clavulanic acid and once with resistance to gentamicin.
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