Sentence examples for frequent promoter from inspiring English sources

CONCLUSIONS: Association of frequent promoter hypermethylation and gene silencing with poor survival, combined with growth suppression of HNSCC cells after forced gene expression, supports the hypothesis that galanin acts as a tumor suppressor.

In fact frequent promoter hypermethylation of Tcf21 was reported in primary lung adenocarcinomas [35].

The CCAAT box is one of the most frequent promoter elements, being found in 60 70% of them by bioinformatic analysis [21] [23] and ChIP on chip experiments [24].

Simply having less frequent promoter bursts at a fixed low rate is expected to yield expression distributions where many cells do not contain detectable levels of the protein of interest [38], [81], [82].

Highly frequent promoter methylation was observed in NSCLC.

Finally, TLR9 frequent promoter polymorphisms associated with IBD might up-regulate TLR9 gene expression [ 31, 32].

This is the first study demonstrating frequent DAB2 promoter hypermethylation in human cancer.

Frequent ID4 promoter methylation was observed in primary breast cancer samples (69%, 117/170).

However, frequent BNC1 promoter methylation (>60 %) in a small cohort of breast tumours has previously been reported [ 64].

We previously reported that frequent CpG promoter hypermethylation was associated with high folate levels in CRC (Kawakami et al, 2003).

Positive T-DMRs are found more frequent in promoter regions than negative T-DMRs, as well as in DHS regions.