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Although all patients agreed to wear the actigraphs, twelve actigraphs were worn for less than 48 hours and/or had frequent missing observations due to instrument malfunction.
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* Selection of most frequent unbearable symptoms: symptoms which were unbearable (score 4 or 5) in at least 15% (9 patients) in the last interview for all patients with at least one interview; between 0 2 missing observations per symptom; three missing observations for overall unbearable suffering.
*Level of university education: 10 missing observations in Germany and 6 missing observations in Austria.
Third, all relevant variables are screened for missing observations.
The last observation carried forward (LOCF) was used to analyze missing observations.
We propose a new and computationally efficient forward backward algorithm for HSMM with missing observations and multiple observation sequences.
The effects of missing observations on complete and partial diallel cross designs are examined.
*Three missing observations.
Some variables have missing observations.
cN = 3 with missing observations.
dN = 6 with missing observations.
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