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Luminal A tumors were characterized by more frequent losses on 16q, while other GISTIC regions were less frequently altered compared to HER2+ tumors.
Mutations in FGFR3, PIK3CA and TP53 are frequently observed and several recurrent copy number aberrations have been identified including frequent losses of chromosome arms 2q, 8p, 9p and 9q, as well as gains of 1q and 6p.
Starting in the early 1990's, however, the strategy declined in profitability and then began posting frequent losses.
Over the past three weeks, as the Yankees spiraled down in the American League East and wild-card races, the frequent losses challenged Manager Joe Girardi's optimistic nature.
"I'm out here on six miles of copper lines, so there's a lot of noise in there," said Mr. Lake, referring to the frequent losses of computer connections.
When they lost their key free agent acquisition Andre Iguodala to a hamstring injury early in the season, the Warriors seemed to have reverted back to the entertaining all-offense, no-defense team they had been in the past, scoring 100+ points a night while still taking frequent losses.
Overall the distribution of the introns does not appear to follow evolutionary lineages suggesting the possibility of rare horizontal gains and frequent losses.
His gambling and betting on billiard games were a huge drain on his funds because of his frequent losses.
Similar(3)
It isn't just Brown's frequent loss of temper that constitutes his bullying.
The frequent loss of possession probably played a big part in Joe Allen hitting a late equaliser.
When it was illegal and unfinanced, we paid for it through expensive hospitalization and frequent loss of life.
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