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We also found that the most frequent lipid abnormalities in youth with type 1 diabetes compared with nondiabetic control subjects are elevated apoB levels and an increased proportion with small, dense LDL particles.
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The most frequent lipid abnormality in the two groups was high LDL-cholesterol (46.4% (NNRTI) vs 54.5% (PI)).
Our data indicated that overlap of lipid abnormalities was frequent, as in the total cohort 41.2% of patients had two or three lipid abnormalities at the same time.
Amongst the risk factors examined for CAD, the study showed older age, higher BMI, more frequent hypertension, higher systolic BP, and lipid abnormalities in the group with diabetes when compared with the group without diabetes.
Previous studies have demonstrated lipid abnormalities to be more frequent in NNRTI than in ART-naïve patients in this setting, 19 precluding the need for an ART-naïve control group in the present study.
Others have reported on the more frequent occurrence of the individual components of the metabolic syndrome (hypertension, diabetes, lipid abnormalities, obesity) [ 9, 10, 15- 18].
Lipid abnormalities associated with antiretroviral therapy in people with HIV infection are more frequent with protease inhibitors (PI -based regimens.
However, no study has explored the interaction between OSAS and smoking on glucose and lipid abnormalities.
Tolonen, N. et al. Lipid abnormalities predict progression of renal disease in patients with type 1 diabetes.
The relationship between lipid abnormalities and the development of aortic stenosis has been recognized for many years.
No differences between early preterm and term pregnancies were observed when TNF-α or target lipid abnormalities occurred in isolation.
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