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In this current study we have used a cutoff score at the middle of the scale, i.e. 50, to distinguish elderly who have frequent limitations (limitations a good bit of the time or more frequently) from those with less frequent limitations.
Frequent limitations are failure to control for potential confounders, lack of validated, long-term end-points, and lack of analysis based on surgeons' individual surgical volumes.
Few other studies have aimed at mapping QTLs for the same production traits, despite frequent limitations for collecting data for a number of individuals that would be optimal for QTL mapping.
We therefore used health plan disenrollment as a proxy for death, as we believe that few patients with metastatic breast cancer are likely to change health plans, due to frequent limitations on coverage of pre-existing conditions.
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Moving the relevant information from research centers to extension agents, policy makers and farmers has been a more frequent limitation.
A frequent limitation to the practical use of the findings of landscape ecological studies is that they tend to focus on the identification and computation of indicators rather than on their interpretation and assessment.
A frequent limitation in these investigations is the ability to accurately quantify the phenotype of interest.
Another frequent limitation is that a family history of a particular disease is often provided by the study subjects themselves without independent verification.
It is noteworthy that pulmonary artery hypertension and/or right ventricular failure may be an even more frequent limitation of ΔRESPPP in case of later or more severe ARDS (PaO2/FiO2 <70) than patients whom we included.
Lack of power of individual studies to detect effects is commonly associated with small sample size, which is a frequent limitation in cognition-based interventions for people with mild AD or VaD.
This is a frequent limitation of mapping-models; 3, 11, 19 however, it implies that the mapping models presented in this study may have a limited ability to predict utility scores for more severe conditions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com