Sentence examples for frequent genetic polymorphisms from inspiring English sources
Frequent genetic polymorphisms and wide (ten to a hundred fold) variability in enzyme expression of the cytochrome P450 superfamily of enzymes (CYPs) are common and may considerably modify enzyme activity, causing large interindividual variability in the rate of product formation.
SNPs are the most frequent type of genetic polymorphism found when resequencing genomes from a common ancestor [ 20] and single mutations in the coding regions can result in significant changes for the phenotype of the cell lines.
The first is that C to T conversions are the most frequent genetic point mutation, small nucleotide polymorphism (SNP), known to occur in a nearly order of magnitude greater frequency than any other SNP [ 24].
Polymorphism p.G71R is the most frequent genetic cause of GS in Asian populations with a frequency of 11%-21 11%-21le Nucleotide Polymorphism Database [dbSNP]).
Unlike the cytochrome P450 enzymes discussed above, genetic polymorphisms in TPMP are less frequent (8-10% for individuals heterozygous for *3A and *3C).
Several common single nucleotide polymorphisms (SNPs) in the EPHX1 gene have been reported previously for the effects of EPHX1 genetic polymorphisms on the maintenance doses of warfarin; among these polymorphisms, the most frequent functional polymorphisms are rs4653436 A>G and rs2292566 G>A [ 14, 21, 22].
The 677C>T polymorphism is of particular interest as it is recognized as the most frequent genetic cause of homocysteinemia [22,23].
Tumors acquire frequent genetic and epigenetic alterations, which can substantially affect gene expression (Raval et al. 2007; Smith et al. 2006) and consequently obscure the association between germline genetic polymorphisms and gene expression (Curtis et al. 2012).
Much of this variability can be attributed to genetic polymorphisms.
Common genetic polymorphisms of GAS6 gene have previously been reported.
Several genetic polymorphisms in vasculitis have now been described.
