'Binding' (32.6%) and 'catalytic activity' (31.6%) were the most frequent functions of the FLcDNAs.
An overview of the most frequent functions of species-specific repeats associated with genes (class III) is shown in Table 1.
The theory presented here clearly moves the concept of health away from a central focus on disease or what is typical or most frequent functioning of internal biological parts and processes.
Possibly multiple functions are then assigned to each protein P i using a guilt-by-association principle, e.g. by looking up in a curated database the most frequent functions of the proteins P j 's that interact with P i with high scores (Butte and Kohane, 2006; Clare and King, 2003; Margolin et al., 2006; Markowetz et al., 2007).
The number of slides that the learners read from 120 to 179 s and from 10 to 59 s promoted the frequent use of the marker function; however, the numbers of pages that learners read from 180 to 239 s, from 240 to 299 s, and over 600 s inhibited the use of the marker function.
Presumably, those widowed individuals that are able to adjust relatively well over time and do not need a specific intervention to regain pre-bereavement levels of functioning, do not make frequent use of the health care services related to their bereavement as well.
Insulinomas are the most frequent functioning pancreatic tumours accounting for 60% of all islet cell tumours [ 1].
GO annotation distribution showed that the most frequent molecular functions of the identified defense-related genes were hydrolases, protein binding, transferases, and transporters.
The most frequent molecular functions of AM proteins are receptor- or kinase-activity within signal transduction pathways (20% each), nucleic acid binding (17%), transcription factor activity (9%) (Additional file 2); their most frequent subcellular localizations are the nucleus (51%), the plasma membrane (43%), and mitochondria (10%) (Additional file 2).
Frequent loss of function of E-cadherin in CLL specimens and the activation of the wnt pathway highlights its role in CLL biology [ 14].
