Normal senescence-related changes in sleep architecture and circadian rhythms must be considered, as well as the frequent medical comorbidities that may affect sleep.
However, the decision to operate on elderly patients for symptomatic AS raises specific problems, particularly related to the frequent concomitant comorbidities that can worsen the outcomes of elderly patients suffering from severe aortic stenosis.
It is not clear, however, whether this program would be effective in the much larger group of patients (mostly women) with fibromyalgia, who have chronic pain and frequent psychiatric comorbidities that might make them more vulnerable to the abuse potential of sodium oxybate.
Services will need to expand to address the specific needs of people aged 50 years and older living with HIV, in managing their ART, as well as the comorbidities that are more frequent among people in this age group.
Furthermore, the real impact of cancer symptoms and the harms and benefits of specific treatments in terms of quality of life may be confounded by the comorbidities, that are typically frequent and clinically significant in this category of patients [ 4].
An additional €3.5 billion was attributable to comorbidities that are more frequent among diabetic patients, particularly the most disadvantaged, such as cancer and obesity [ 41]. *Expenditure related to pathologies frequently found in patients with diabetes (e.g., certain cancers, obesity).
Neither could Bevan could have foreseen that the NHS would become a victim of its own success: enabling us to live longer, but often with the chronic conditions and comorbidities that can accompany old age.
Because some of the patients could have strabismus (i.e., a frequent comorbidity in CP that can reduce visual acuity in one eye), the color measurements were performed under three conditions: binocularly and monocularly for the right and left eyes.A psychophysical staircase procedure was used for threshold determination along the protan, deutan, and tritan confusion axes.
More recent studies have found that the most frequent comorbidities were diabetes (19 37%) [ 19- 21], obesity (17 31%) [ 20, 21], hypertension (35%) [ 20] and intravenous drug abuse (30%) [ 19].
It is increasingly evident that FM represents a significant challenge in view of its high prevalence, frequent comorbidities, and frustration with current treatment modalities.
